Modeling inhalation anthrax infection: a research journey

Judy Day (May 6, 2020)

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From work initiated at the Mathematical Biosciences Institute, a mathematical model was published in 2011 that investigated the immune response to inhalation anthrax infection. That publication led to a collaboration with the U.S. Environmental Protection Agency which blossomed into a Investigative Working Group effort supported by the National Institute for Mathematical and Biological Synthesis. This group included experts from both the anthrax research community as well as mathematical modelers. Over a period of several years, members of this group explored the utility of mathematical modeling in understanding risk in low dose inhalation anthrax infection. This poster describes the journey of the research that was inspired by these events and discusses the results and relationships it generated.